SCHEMBL14680432

SCHEMBL14680432

Cc1cccc(C)c1-c1ccc(B2OC(C)(C)C(C)(C)O2)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 4/20 0.37
LIPG Q9Y5X9 4/20 0.37
JAK2 O60674 1/20 0.34
BTK Q06187 1/20 0.34
ANPEP P15144 1/20 0.33
LAP3 P28838 1/20 0.33
MYC P01106 1/20 0.33
CYP2A6 P11509 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CES2 O00748 1/20 0.30
KDM1A O60341 1/20 0.30
EED O75530 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
CES1 P23141 1/20 0.30
PTPN6 P29350 1/20 0.30
BLM P54132 1/20 0.30
PTPN11 Q06124 1/20 0.30
SUZ12 Q15022 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14680356 0.88 JAK2 (0.32) LPLLIPGJAK2BTKCES2
SCHEMBL13855166 0.87 LPL (0.41) LPLLIPGJAK2BTKANPEP
SCHEMBL21888685 0.86 LPL (0.38) LPLLIPGJAK2BTKANPEP
SCHEMBL16553033 0.85 LPL (0.44) LPLLIPGJAK2BTKANPEP
SCHEMBL18194212 0.85 LPL (0.44) LPLLIPGJAK2BTKANPEP
SCHEMBL16553054 0.83 LPL (0.41) LPLLIPGJAK2BTKANPEP
SCHEMBL21888372 0.83 JAK2 (0.40) LPLLIPGJAK2BTK
SCHEMBL2027186 0.83 LPL (0.48) LPLLIPGJAK2BTKANPEP
SCHEMBL21888445 0.82 LIPG (0.45) LPLLIPGJAK2BTKANPEP
SCHEMBL17322311 0.82 CYP1A2 (0.48) LPLLIPGJAK2BTKANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-11 US disclosed
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-11 US disclosed
EP-2788306-B1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KK (JP) 2017-05-03 EP disclosed
US-9590199-B2 Organic compound, organic light emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2017-03-07 US disclosed
US-9590199-B2 Organic compound, organic light emitting device, and image display device CANON KABUSHIKI KAISHA (JP) 2017-03-07 US disclosed
US-8963813-B2 Organic compound and organic light emitting device having the same CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-8963813-B2 Organic compound and organic light emitting device having the same CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-20140374723-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2014-12-25 US disclosed
US-20140374723-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2014-12-25 US disclosed
WO-2013084833-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2013-06-13 WO disclosed
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-07 US disclosed
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME TRPA1, OCIAD1, BMP2 LPL 2035/4885LIPG 3029/4885JAK2 3587/4885
US-20170133598-A1 NOVEL ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE, AND IMAGE DISPLAY DEVICE OCIAD1, OCIAD2, OXER1 LPL 2620/4885LIPG 3086/4885JAK2 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.