Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.45 |
| ▸ | WNT3A | P56704 | 4/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30308690 | 0.86 | DYRK1A (0.65) | DYRK1AMAP4K4UHRF1CDC7ROCK2 | |
| SCHEMBL1896511 | 0.86 | DYRK1A (0.65) | DYRK1AMAP4K4UHRF1CDC7ROCK2 | |
| SCHEMBL6855459 | 0.84 | DYRK1A (0.66) | DYRK1AMAP4K4UHRF1CDC7ROCK2 | |
| Iodide SCHEMBL9618570 | 0.84 | DYRK1A (0.63) | DYRK1AMAP4K4UHRF1CDC7ROCK2 | |
| SCHEMBL8964255 | 0.82 | DYRK1A (0.62) | DYRK1AMAP4K4UHRF1PSEN1PSEN2 | |
| SCHEMBL31119862 | 0.82 | DYRK1A (0.62) | DYRK1AMAP4K4UHRF1PSEN1PSEN2 | |
| SCHEMBL1798186 | 0.81 | DYRK1A (0.61) | DYRK1AMAP4K4UHRF1PSEN1PSEN2 | |
| SCHEMBL1492706 | 0.81 | DYRK1A (0.61) | DYRK1AMAP4K4UHRF1CDC7ROCK2 | |
| SCHEMBL2615984 | 0.81 | DYRK1A (0.61) | DYRK1AMAP4K4UHRF1CDC7ROCK2 | |
| SCHEMBL430984 | 0.81 | DYRK1A (0.61) | DYRK1AMAP4K4UHRF1CDC7ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796461-B2 | 1,2,4,5-substituted phenyl compound, method for producing same and organic electroluminescent device comprising same as constituent | TOSOH CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8796461-B2 | 1,2,4,5-substituted phenyl compound, method for producing same and organic electroluminescent device comprising same as constituent | TOSOH CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | TOSOH CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | TOSOH CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | XDH, OR10J3, HAX1 | DYRK1A 4243/4885MAP4K4 3989/4885UHRF1 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.