Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099429 | 0.84 | ESR1 (0.64) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9355632 | 0.83 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289841 | 0.83 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19406565 | 0.83 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289817 | 0.83 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289766 | 0.83 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289827 | 0.83 | ESR1 (0.77) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL14207539 | 0.82 | LMNA (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289821 | 0.82 | ESR1 (0.74) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28111428 | 0.81 | LMNA (0.59) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130032791-A1 | CONJUGATED POLYMERS HAVING AN IMINE GROUP AT THE INTRACHAIN ELECTRON DONOR BRIDGEHEAD POSITION USEFUL IN ELECTRONIC DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130032791-A1 | CONJUGATED POLYMERS HAVING AN IMINE GROUP AT THE INTRACHAIN ELECTRON DONOR BRIDGEHEAD POSITION USEFUL IN ELECTRONIC DEVICES | ICMT, INMT, INCENP | ESR1 85/4885AKR1C4 2658/4885AKR1C3 3386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.