Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PGD | P52209 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19846203 | 0.88 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL4953255 | 0.86 | MMP1 (0.50) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL19846200 | 0.86 | MMP1 (0.50) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL29098552 | 0.83 | ALDH1A1 (0.43) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1168152 | 0.82 | MMP1 (0.42) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL23630284 | 0.80 | TSHR (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL6892557 | 0.80 | MMP1 (0.67) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL12091193 | 0.80 | MMP1 (0.45) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL20590957 | 0.79 | LMNA (0.55) | TSHRMEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL19846192 | 0.78 | MMP1 (0.44) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150196568-A1 | SYSTEM FOR USE BY COMPOUNDING PHARMACISTS TO PRODUCE HORMONE REPLACEMENT MEDICINE CUSTOMIZED FOR EACH CUSTOMER | MAMCHUR STEPHEN A (CA) | 2015-07-16 | — | — | US | disclosed |
| US-20110071122-A1 | System for use by compounding pharmacists cists to produce hormone replacement medicine customized for each customer | MAMCHUR STEPHEN A | 2011-03-24 | — | — | US | disclosed |
| US-7858607-B2 | System for use by compounding pharmacists to produce hormone replacement medicine customized for each consumer | MAMCHUR STEPHEN A | 2010-12-28 | — | — | US | disclosed |
| US-20040180866-A1 | Hormone concentrate pharmaceutical composition | MAMCHUR STEPHEN A (CA) | 2004-09-16 | — | — | US | disclosed |