Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468582 | 0.91 | RXRA (0.43) | RXRARXRBRXRGPARP1SMN1; SMN2 | |
| Iodide SCHEMBL1468441 | 0.90 | RXRA (0.43) | RXRARXRBRXRGPARP1SMN1; SMN2 | |
| SCHEMBL1468193 | 0.87 | CYP4Z1 (0.41) | PARP1ADRA1AHTR1ANPC1RAB9A | |
| SCHEMBL1470232 | 0.86 | MLNR (0.41) | PARP1SMN1; SMN2NFKB1LMNACYP2D6 | |
| SCHEMBL1468452 | 0.84 | PPARD (0.43) | PARP1SMN1; SMN2NFKB1LMNACYP2D6 | |
| SCHEMBL1468427 | 0.84 | FAAH (0.43) | PARP1ALDH1A1S1PR1ADRA1AHTR1A | |
| SCHEMBL1468719 | 0.84 | FAAH (0.43) | PARP1ALDH1A1S1PR1ADRA1AHTR1A | |
| SCHEMBL1468653 | 0.84 | NPC1 (0.41) | PARP1SMN1; SMN2NFKB1LMNACYP2D6 | |
| SCHEMBL1470274 | 0.82 | PARP1 (0.40) | RXRARXRBRXRGPARP1SMN1; SMN2 | |
| SCHEMBL1468602 | 0.80 | RAB9A (0.60) | RXRARXRBRXRGSMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722723-B2 | Aromatic amide derivative | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071304-A1 | AROMATIC AMIDE DERIVATIVE | NCOR2, NCOR1, EP300 | RXRA 241/4885RXRB 285/4885RXRG 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.