Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31696760 | 0.77 | MAPT (0.47) | KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL20599056 | 0.71 | S100A4 (0.46) | NPBWR1ALDH1A1 | |
| SCHEMBL14996550 | 0.68 | HSD11B1 (0.54) | HSD11B1CRHR1KMT2AALDH1A1USP2 | |
| SCHEMBL15331519 | 0.67 | SMN1; SMN2 (0.40) | HSD11B1CRHR1NPBWR1NR2F2KMT2A | |
| SCHEMBL15330034 | 0.67 | CYP1A2 (0.40) | HSD11B1CRHR1NPBWR1NR2F2KMT2A | |
| SCHEMBL4032763 | 0.67 | HSD11B1 (0.49) | HSD11B1CRHR1KMT2AALDH1A1USP2 | |
| SCHEMBL22658975 | 0.67 | HSD11B1 (0.41) | HSD11B1CRHR1KMT2AMEN1 | |
| SCHEMBL7707702 | 0.67 | KMO (0.42) | HSD11B1CRHR1 | |
| SCHEMBL16347107 | 0.66 | KMT2A (0.48) | HSD11B1KMT2A | |
| SCHEMBL12297649 | 0.66 | HSD11B1 (0.40) | HSD11B1CRHR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |