SCHEMBL1469447

SCHEMBL1469447

CCOC(C)COC(=O)OCC(C)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
SOAT1 P35610 1/20 0.39
LMNA P02545 3/20 0.38
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
NFKB1 P19838 1/20 0.35
PTGS1 P23219 1/20 0.35
APEX1 P27695 1/20 0.35
THPO P40225 1/20 0.35
PMP22 Q01453 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALOX15 P16050 1/20 0.33
THRB P10828 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1470043 0.96 ALDH1A1 (0.56) ALDH1A1SOAT1LMNATSHRTDP1
SCHEMBL1470058 0.91 ALDH1A1 (0.39) ALDH1A1SOAT1LMNATSHRTDP1
SCHEMBL1469882 0.87 ALDH1A1 (0.44) ALDH1A1LMNATSHRTDP1SMN1; SMN2
SCHEMBL15503269 0.86 ALDH1A1 (0.34) ALDH1A1SOAT1LMNATSHRSMN1; SMN2
SCHEMBL12751992 0.85 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL2777851 0.84 ALDH1A1 (0.50) ALDH1A1LMNATSHRTDP1MEN1
SCHEMBL14905777 0.84 LMNA (0.36) ALDH1A1SOAT1LMNATSHRTDP1
SCHEMBL17150351 0.84 LMNA (0.36) ALDH1A1SOAT1LMNATSHRTDP1
SCHEMBL1471555 0.84 NAAA (0.46) ALDH1A1LMNATSHRMAPT
SCHEMBL445901 0.82 NAAA (0.38) ALDH1A1SOAT1LMNATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871965-B2 Method for producing urethanes BASF SE (DE) 2014-10-28 US claimed
EP-2491011-A1 METHOD FOR PRODUCING URETHANES BASF SE (DE) 2012-08-29 EP claimed
US-20120203022-A1 METHOD FOR PRODUCING URETHANES BASF SE (DE) 2012-08-09 US claimed
WO-2011048124-A1 METHOD FOR PRODUCING URETHANES BASF SE (DE) 2011-04-28 WO claimed
EP-3249735-A2 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING THE SAME Mitsubishi Chemical Corporation (JP) 2017-11-29 EP disclosed
US-9231274-B2 Nonaqueous electrolyte solution and lithium secondary battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2016-01-05 US disclosed
US-9136560-B2 Nonaqueous electrolyte solution and lithium secondary battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2015-09-15 US disclosed
US-8871965-B2 Method for producing urethanes BASF SE (DE) 2014-10-28 US disclosed
US-20130196225-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2013-08-01 US disclosed
US-8435681-B2 Nonaqueous electrolyte solution and lithium secondary battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2013-05-07 US disclosed
US-20130095379-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME KOTATO MINORU (JP) 2013-04-18 US disclosed
US-20120244426-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-27 US disclosed
EP-2491011-A1 METHOD FOR PRODUCING URETHANES BASF SE (DE) 2012-08-29 EP disclosed
US-20120203022-A1 METHOD FOR PRODUCING URETHANES BASF SE (DE) 2012-08-09 US disclosed
US-8043745-B2 Non-aqueous electrolyte solution and lithium secondary battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-10-25 US disclosed
US-8007938-B2 Nonaqueous electrolyte solution and lithium secondary battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-30 US disclosed
WO-2011048124-A1 METHOD FOR PRODUCING URETHANES BASF SE (DE) 2011-04-28 WO disclosed
US-20110070485-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2011-03-24 US disclosed
US-20070224514-A1 Nonaqueous Electrolyte Solution and Lithium Secondary Battery Using Same MITSUBISHI CHEMICAL CORPORATION (JP) 2007-09-27 US disclosed
EP-1744394-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2007-01-17 EP disclosed