SCHEMBL14698331

SCHEMBL14698331

CNC(=O)c1cc(-n2cncn2)cc(C)c1NC(=O)c1cnn(CC(F)(F)F)c1-c1ncccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MALT1 Q9UDY8 4/20 0.34
▸ NTRK1 P04629 9/20 0.33
▸ RAB9A P51151 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.32
▸ KAT7 O95251 1/20 0.32
▸ KAT6A Q92794 1/20 0.32
▸ KAT5 Q92993 1/20 0.32
▸ KAT8 Q9H7Z6 1/20 0.32
▸ TTK P33981 1/20 0.32
▸ F9 P00740 1/20 0.31
▸ SCN5A Q14524 1/20 0.31
▸ SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698445 0.81 ALDH1A1 (0.39) NTRK1
SCHEMBL14698293 0.81 MALT1 (0.34) MALT1SCN5ASCN9A
SCHEMBL14698291 0.81 MALT1 (0.34) MALT1SCN5ASCN9A
SCHEMBL14698209 0.72 SCN5A (0.31) RAB9ASCN5ASCN9A
SCHEMBL14698210 0.72 SCN5A (0.31) RAB9ASCN5ASCN9A
SCHEMBL14698211 0.72 SCN5A (0.31) RAB9ASCN5ASCN9A
SCHEMBL10124234 0.72 DHODH (0.30) —
SCHEMBL14697943 0.71 KDM4E (0.41) SCN5ASCN9A
SCHEMBL14698223 0.71 METAP2 (0.38) MALT1SCN5ASCN9A
SCHEMBL19461184 0.70 ENPP2 (0.32) MALT1NTRK1KAT7KAT6AKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-19 — — US disclosed
EP-2742038-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-18 — — EP disclosed
WO-2013024006-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES ANTXR2, NQO2, AAAS MALT1 2645/4885NTRK1 3776/4885RAB9A 1446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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