SCHEMBL14698210

SCHEMBL14698210

Cc1cc(Cl)cc(C(=O)/N=S2/CCSC2)c1NC(=O)c1cnn(CC(F)(F)F)c1-c1ncccc1Cl

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SCN5A Q14524 1/20 0.31
▸ SCN9A Q15858 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ JAK2 O60674 1/20 0.31
▸ JAK1 P23458 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698211 1.00 SCN5A (0.31) SCN5ASCN9ARAB9ASMN1; SMN2JAK2
SCHEMBL14698209 1.00 SCN5A (0.31) SCN5ASCN9ARAB9ASMN1; SMN2JAK2
SCHEMBL14698293 0.73 MALT1 (0.34) SCN5ASCN9AJAK2JAK1
SCHEMBL14698291 0.73 MALT1 (0.34) SCN5ASCN9AJAK2JAK1
SCHEMBL14698331 0.72 MALT1 (0.34) SCN5ASCN9ARAB9A
SCHEMBL14698320 0.71 TRPV1 (0.39) —
SCHEMBL14697943 0.69 KDM4E (0.41) SCN5ASCN9ASMN1; SMN2
SCHEMBL14698223 0.69 METAP2 (0.38) SCN5ASCN9ASMN1; SMN2
SCHEMBL14697956 0.68 ALDH1A1 (0.47) RAB9ASMN1; SMN2
SCHEMBL14698109 0.62 METAP2 (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2742027-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-18 — — EP disclosed
US-20140162875-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides BASF SE (DE) 2014-06-12 — — US disclosed
WO-2013024004-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140162875-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides ANTXR2, NIT2, TXN SCN5A 200/4885SCN9A 719/4885RAB9A 2088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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