SCHEMBL1469834

SCHEMBL1469834

CCCCCCNC(CC)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.48
ELANE P08246 3/20 0.45
ALDH1A1 P00352 2/20 0.44
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 1/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
MGLL Q99685 1/20 0.41
HDAC3 O15379 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1470251 0.95 ELANE (0.47) NAAAELANEALDH1A1RAB9ASMN1; SMN2
SCHEMBL1471894 0.84 ELANE (0.51) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL1470281 0.80 ELANE (0.53) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL1471982 0.79 ALDH1A1 (0.51) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL8375161 0.78 ELANE (0.50) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL8371946 0.78 ELANE (0.50) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL7611800 0.78 ELANE (0.50) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL28629364 0.76 ALDH1A1 (0.51) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL27868074 0.76 ELANE (0.49) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL8925288 0.76 ELANE (0.49) ELANEALDH1A1RAB9ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2130817-B1 Polymerizable Type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2016-01-06 EP disclosed
CN-102056890-B Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV 2015-02-04 CN disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
WO-2009147054-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
WO-2009147057-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
EP-2130818-A1 Multifunctional Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed
EP-2130817-A1 Polymerizable Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CRKL, CYTH2, CCNH NAAA 4360/4885ELANE 4060/4885ALDH1A1 1579/4885
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CCNH, CRKL, ERH NAAA 3905/4885ELANE 4439/4885ALDH1A1 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.