SCHEMBL1471894

SCHEMBL1471894

CCNC(CC)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.51
ALDH1A1 P00352 4/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
SRD5A2 P31213 1/20 0.47
GAA P10253 2/20 0.45
HTT P42858 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
LMNA P02545 2/20 0.45
MAPK1 P28482 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 2/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1470281 0.87 ELANE (0.53) ELANEALDH1A1RAB9ASMN1; SMN2SRD5A2
SCHEMBL1470251 0.86 ELANE (0.47) ELANEALDH1A1RAB9ASMN1; SMN2SRD5A2
SCHEMBL1471982 0.85 ALDH1A1 (0.51) ELANEALDH1A1RAB9ASMN1; SMN2SRD5A2
SCHEMBL1469834 0.84 NAAA (0.48) ELANEALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL16606087 0.82 MTNR1A (0.42) ALDH1A1LMNA
SCHEMBL14723237 0.80 ELANE (0.58) ELANEALDH1A1RAB9ASMN1; SMN2SRD5A2
SCHEMBL7716884 0.77 SMN1; SMN2 (0.58) ELANESMN1; SMN2SRD5A2
SCHEMBL29009109 0.77 ELANE (0.59) ELANEALDH1A1RAB9ASMN1; SMN2SRD5A2
SCHEMBL18978115 0.74 KMT2A (0.69) ELANEALDH1A1SRD5A2GAALMNA
SCHEMBL1534312 0.74 KMT2A (0.69) ELANEALDH1A1SRD5A2GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2130817-B1 Polymerizable Type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2016-01-06 EP disclosed
CN-102056892-B Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV 2015-07-22 CN disclosed
CN-102056890-B Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV 2015-02-04 CN disclosed
US-8389769-B2 Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-03-05 US disclosed
US-8362101-B2 Multifunctional type II photoinitiators and curable compositions AGFA GRAPHICS NV (BE) 2013-01-29 US disclosed
CN-102056890-A Polymerizable type II photoinitiators and curable compositions AGFA GRAPHICS NV 2011-05-11 CN disclosed
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-24 US disclosed
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-03-17 US disclosed
WO-2009147054-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
WO-2009147057-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2009-12-10 WO disclosed
EP-2130818-A1 Multifunctional Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed
EP-2130817-A1 Polymerizable Type II photoinitiators and curable compositions AGFA Graphics NV (BE) 2009-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110069130-A1 MULTIFUNCTIONAL TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CRKL, CYTH2, CCNH ELANE 4060/4885ALDH1A1 1579/4885RAB9A 2747/4885
US-20110063388-A1 POLYMERIZABLE TYPE II PHOTOINITIATORS AND CURABLE COMPOSITIONS CCNH, CRKL, ERH ELANE 4439/4885ALDH1A1 1584/4885RAB9A 2764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.