SCHEMBL14698779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14706984	0.93	NPC1 (0.55)	HSD17B3ALDH1A1LMNAMAPTHPGD
	SCHEMBL14698913	0.86	NPC1 (0.54)	HSD17B3HDAC1HDAC6HDAC8HDAC2
	SCHEMBL14697567	0.83	NPC1 (0.63)	NOTUMHSD17B3HDAC1HDAC6HDAC8
	SCHEMBL3266328	0.80	ALDH1A1 (0.66)	ALDH1A1LMNAMAPTHPGDHTT
	SCHEMBL14699577	0.77	NPC1 (0.77)	NOTUMHSD17B3ALDH1A1LMNAMAPT
	SCHEMBL2086851	0.72	BCHE (0.67)	ALDH1A1LMNAMAPT
	SCHEMBL9442261	0.71	NOTUM (0.59)	NOTUMHSD17B3HDAC1HDAC6HDAC8
	SCHEMBL16817949	0.69	NOTUM (0.56)	NOTUMHSD17B3HDAC1HDAC6HDAC8
	SCHEMBL6961286	0.68	NOTUM (0.48)	NOTUMHSD17B3HDAC1HDAC6HDAC8
	SCHEMBL14699571	0.68	NPC1 (0.77)	HSD17B3HDAC1HDAC6HDAC8HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.