SCHEMBL14698798

SCHEMBL14698798

NC(=O)CNc1ccccc1C(N)=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
KDM4E B2RXH2 8/20 0.50
RAB9A P51151 2/20 0.50
SIRT2 Q8IXJ6 4/20 0.49
ALDH1A1 P00352 5/20 0.47
HPGD P15428 2/20 0.47
POLB P06746 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
MAPT P10636 2/20 0.45
HSD17B10 Q99714 2/20 0.45
TSHR P16473 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
NPC1 O15118 1/20 0.45
TP53 P04637 1/20 0.45
PKM P14618 1/20 0.45
NFKB1 P19838 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1499127 0.87 AGTR1 (0.60) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL6018454 0.85 AGTR1 (0.48) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL8943473 0.84 AGTR1 (0.57) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL11667793 0.82 KMT2A (0.52) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL31326903 0.82 AGTR1 (0.60) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL6294346 0.82 AGTR1 (0.56) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL3413963 0.82 AGTR1 (0.56) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL8047226 0.82 KMT2A (0.56) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL3441356 0.81 AGTR1 (0.54) AGTR1MEN1KMT2AKDM4ERAB9A
SCHEMBL30311518 0.79 HSD17B10 (0.63) AGTR1MEN1KMT2AKDM4ESIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140243197-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2014-08-28 US disclosed
US-20140243196-A1 Carbamoylmethoxy- and Carbamoylmethylthio- and Carbamoylmethylamino Benzamides for Combating Invertebrate Pests BASF SE (DE) 2014-08-28 US disclosed
US-20140243196-A1 Carbamoylmethoxy- and Carbamoylmethylthio- and Carbamoylmethylamino Benzamides for Combating Invertebrate Pests BASF SE (DE) 2014-08-28 US disclosed
US-20140200135-A1 Carbamoylmethoxy- and carbamoylmethylthio- and carbamoylmethylamino benzamides for combating invertebrate pests BASF SE (DE) 2014-07-17 US disclosed
EP-2744784-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2014-06-25 EP disclosed
EP-2744782-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2014-06-25 EP disclosed
EP-2744785-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2014-06-25 EP disclosed
CN-103889959-A Carbamoylmethoxy-and carbamoylmethylthio-and carbamoylmethylaminobenzamides for controlling invertebrate pests BASF SE 2014-06-25 CN disclosed
CN-103889960-A Carbamoylmethoxy- and carbamoylmethylthio- and carbamoylmethylamino benzamides for combating invertebrate pests BASF SE 2014-06-25 CN disclosed
CN-103889956-A Carbamoylmethoxy- and carbamoylmethylthio- and carbamoylmethylamino benzamides for combating invertebrate pests BASF SE 2014-06-25 CN disclosed
WO-2013024170-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024169-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024171-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2013-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243196-A1 Carbamoylmethoxy- and Carbamoylmethylthio- and Carbamoylmethylamino Benzamides for Combating Invertebrate Pests BCHE, GNMT, PTMS AGTR1 2115/4885MEN1 1294/4885KMT2A 207/4885
US-20140200135-A1 Carbamoylmethoxy- and carbamoylmethylthio- and carbamoylmethylamino benzamides for combating invertebrate pests BCHE, GNMT, PTMS AGTR1 2115/4885MEN1 1294/4885KMT2A 207/4885
US-20140243197-A1 CARBAMOYLMETHOXY- AND CARBAMOYLMETHYLTHIO- AND CARBAMOYLMETHYLAMINO BENZAMIDES FOR COMBATING INVERTEBRATE PESTS BCHE, GNMT, PTMS AGTR1 2115/4885MEN1 1294/4885KMT2A 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.