Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11412675 | 0.87 | TDP1 (0.40) | TSHRTDP1FAAHPRSS1PRSS2 | |
| Hydrogen Peroxide SCHEMBL28379963 | 0.82 | — | — | |
| SCHEMBL106433 | 0.82 | — | — | |
| SCHEMBL3808233 | 0.82 | — | — | |
| Benzene SCHEMBL2887752 | 0.80 | TSHR (0.73) | TSHRTDP1FAAHPRSS1PRSS2 | |
| Benzene SCHEMBL17784484 | 0.80 | CA1 (0.42) | TSHRTDP1FAAHPRSS1PRSS2 | |
| Biphenyl SCHEMBL22558772 | 0.78 | ALDH1A1 (0.60) | TDP1FAAHPRSS1PRSS2ELANE | |
| Pyridine SCHEMBL5839188 | 0.78 | NAPRT (0.60) | TSHRTDP1FAAHPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL25173719 | 0.76 | — | — | |
| SCHEMBL4412627 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153836-B | Preparation and application of potassium decafluoro-4- (pentafluoroethyl) cyclohexyl-1-sulfonate | 中船(邯郸)派瑞特种气体股份有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-111153836-A | Preparation and application of potassium decafluoro-4- (pentafluoroethyl) cyclohexyl-1-sulfonate | 中船重工（邯郸）派瑞特种气体有限公司 | 2020-05-15 | — | — | CN | claimed |
| CN-102869360-A | Pharmaceutical compositions and methods for treating hypertension | TSH BIOPHARM COMPANY LTD | 2013-01-09 | — | — | CN | claimed |
| US-4886629-A | Process for the preparation of fluorinated benzene sulfonyl fluorides | ALLIED-SIGNAL INC. (US) | 1989-12-12 | — | — | US | claimed |
| US-20250312347-A1 | THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS | BROWN DENNIS M (US) | 2025-10-09 | — | — | US | disclosed |
| US-12336993-B2 | Therapeutic benefit of suboptimally administered chemical compounds | BROWN DENNIS M (US) | 2025-06-24 | — | — | US | disclosed |
| CN-119876163-A | Nucleoside monomer containing exogenous functional group chemical modification and covalent nucleic acid aptamer containing nucleoside monomer | 浙江工业大学 | 2025-04-25 | — | — | CN | disclosed |
| US-12194002-B2 | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dibromodulcitol | BROWN DENNIS (US) | 2025-01-14 | — | — | US | disclosed |
| US-20240307372-A1 | COMPOSITIONS AND METHODS TO IMPROVE BENEFIT OF SUBOPTIMALLY ADMINISTERED THERAPEUCTICS FOR THE TREATMENT OF BENIGN AND NEOPLASTIC DISEASES, INFECTIONS, INFLAMMATORY, METABOLIC AND IMMUNOLOGIAL DISEASES | Escend Pharmaceuticals, Inc. | 2024-09-19 | — | — | US | disclosed |
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-20230133044-A1 | THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS | BROWN DENNIS M (US) | 2023-05-04 | — | — | US | disclosed |
| US-11491154-B2 | Therapeutic benefit of suboptimally administered chemical compounds | BROWN DENNIS M (US) | 2022-11-08 | — | — | US | disclosed |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | WYETH (US) | 2006-12-07 | — | — | US | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |
| US-6043368-A | Method of making thieno-pyridine derivatives | POLI INDUSTRIA CHIMICA, S.P.A. (IT) | 2000-03-28 | — | — | US | disclosed |
| EP-0829482-A2 | Method of making thieno-pyridine derivatives | Poli Industria Chimica S.p.A. (IT) | 1998-03-18 | — | — | EP | disclosed |
| US-4886629-A | Process for the preparation of fluorinated benzene sulfonyl fluorides | ALLIED-SIGNAL INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4886629-A | Process for the preparation of fluorinated benzene sulfonyl fluorides | ALLIED-SIGNAL INC. (US) | 1989-12-12 | — | — | US | disclosed |
| US-4128586-A | Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols | ALLIED CHEMICAL CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
| US-4127580-A | MULTISTAGE | PARCOR (FR) | 1978-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133044-A1 | THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS | UNG, DPYD, TPMT | TSHR 4307/4885TDP1 201/4885FAAH 3560/4885 |
| US-20250312347-A1 | THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS | UNG, DPYD, TPMT | TSHR 4307/4885TDP1 201/4885FAAH 3560/4885 |
| US-11491154-B2 | Therapeutic benefit of suboptimally administered chemical compounds | UNG, DPYD, TPMT | TSHR 4307/4885TDP1 201/4885FAAH 3560/4885 |
| US-12336993-B2 | Therapeutic benefit of suboptimally administered chemical compounds | UNG, DPYD, TPMT | TSHR 4307/4885TDP1 201/4885FAAH 3560/4885 |
| US-20060276464-A1 | Diarylsulfone sulfonamides and use thereof | SFRP1, SOS1, FZD7 | TSHR 3611/4885TDP1 4520/4885FAAH 3198/4885 |
| US-12194002-B2 | Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dibromodulcitol | HEXD, DDOST, PAICS | TSHR 4583/4885TDP1 1281/4885FAAH 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.