SCHEMBL14701202

SCHEMBL14701202

CN(C)c1ccc(/C=C(\C#N)C(=O)OCCOC(=O)/C(C#N)=C/c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.62
KMT2A Q03164 6/20 0.62
ALDH1A1 P00352 6/20 0.62
PSMD14 O00487 1/20 0.62
DNM1 Q05193 3/20 0.60
MAPT P10636 4/20 0.59
IDE P14735 2/20 0.57
PPARG P37231 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
NCOR2 Q9Y618 1/20 0.55
KDM4E B2RXH2 1/20 0.54
USP2 O75604 1/20 0.54
RECQL P46063 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
RAB9A P51151 1/20 0.54
APP P05067 1/20 0.51
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457218 0.93 MEN1 (0.61) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL21457220 0.93 MEN1 (0.61) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL8385637 0.93 ALDH1A1 (0.58) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL15521575 0.92 MEN1 (0.55) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL2011561 0.91 APP (0.56) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL2011560 0.91 APP (0.56) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL14129149 0.91 MEN1 (0.57) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL2011563 0.91 APP (0.56) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL26382501 0.91 APP (0.56) MEN1KMT2AALDH1A1PSMD14DNM1
SCHEMBL5950335 0.90 ALDH1A1 (0.71) MEN1KMT2AALDH1A1PSMD14MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
EP-2620476-A1 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION Adeka Corporation (JP) 2013-07-31 EP disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 MEN1 2179/4885KMT2A 3478/4885ALDH1A1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.