SCHEMBL5950335

SCHEMBL5950335

CCOC(=O)/C(C#N)=C\c1ccc(N(C)C)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.71
MEN1 O00255 6/20 0.71
KMT2A Q03164 6/20 0.71
PSMD14 O00487 1/20 0.71
MAPT P10636 8/20 0.67
KDM4E B2RXH2 2/20 0.67
PKM P14618 1/20 0.61
HTT P42858 1/20 0.61
L3MBTL1 Q9Y468 3/20 0.60
TDP1 Q9NUW8 2/20 0.60
NPC1 O15118 1/20 0.60
MAPK1 P28482 1/20 0.60
CASP3 P42574 1/20 0.60
RAB9A P51151 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
PDCD1 Q15116 1/20 0.57
CD274 Q9NZQ7 1/20 0.57
CRHBP P24387 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4696359 1.00 ALDH1A1 (0.71) ALDH1A1MEN1KMT2APSMD14MAPT
SCHEMBL4696361 1.00 ALDH1A1 (0.71) ALDH1A1MEN1KMT2APSMD14MAPT
SCHEMBL14625398 0.96 ALDH1A1 (0.67) ALDH1A1MEN1KMT2APSMD14MAPT
SCHEMBL13904928 0.94 ALDH1A1 (0.64) ALDH1A1MEN1KMT2APSMD14MAPT
SCHEMBL15373529 0.92 ALDH1A1 (0.71) ALDH1A1MEN1KMT2APSMD14MAPT
SCHEMBL14701202 0.90 MEN1 (0.62) ALDH1A1MEN1KMT2APSMD14MAPT
SCHEMBL2139676 0.90 ALDH1A1 (0.81) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL4317761 0.90 ALDH1A1 (0.81) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL2139678 0.90 ALDH1A1 (0.81) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL21457218 0.89 MEN1 (0.61) ALDH1A1MEN1KMT2APSMD14MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
US-11827814-B2 Adhesive composition and use thereof SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. 2023-11-28 US disclosed
US-11827814-B2 Adhesive composition and use thereof SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. 2023-11-28 US disclosed
US-20230314675-A1 BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2023-10-05 US disclosed
US-20230314675-A1 BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2023-10-05 US disclosed
US-11732163-B2 2023-08-22 US disclosed
US-11732163-B2 2023-08-22 US disclosed
US-20220002566-A1 Coating Composition LG CHEM, LTD. (KR) 2022-01-06 US disclosed
US-20210054247-A1 Pressure-Sensitive Adhesive Composition LG CHEM, LTD. (KR) 2021-02-25 US disclosed
US-20200332157-A1 Adhesive Composition and Use Thereof LG CHEM, LTD. (KR) 2020-10-22 US disclosed
US-20200181363-A1 BLUE LIGHT BLOCKING SYSTEM CONTAINING PYRAZOLINE OR/AND PHENYLACRYLIC COMPOUNDS EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2020-06-11 US disclosed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181363-A1 BLUE LIGHT BLOCKING SYSTEM CONTAINING PYRAZOLINE OR/AND PHENYLACRYLIC COMPOUNDS CUTA, PASK, SERPINE1 ALDH1A1 217/4885MEN1 1684/4885KMT2A 3225/4885
US-20230314675-A1 BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM CRY1, CRY2, BLVRB ALDH1A1 326/4885MEN1 828/4885KMT2A 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.