SCHEMBL14701241

SCHEMBL14701241

C=C(C)C(=O)OCOC(=O)c1ccc(C(C)(C)O)c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
TSHR P16473 3/20 0.33
ACE2 Q9BYF1 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 3/20 0.31
CNR1 P21554 1/20 0.31
CDC25B P30305 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
CYP3A4 P08684 1/20 0.31
MYC P01106 1/20 0.30
ELANE P08246 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701251 0.88 KCNJ11 (0.35) ADRB2ADRB1ADRB3TSHRKDM4E
SCHEMBL28886899 0.78 TSHR (0.53) TSHRALDH1A1CDC25BCYP3A4
SCHEMBL18904535 0.78 CDC25B (0.52) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL14701245 0.77 KDM4E (0.32) TSHRALDH1A1KDM4EHPGDELANE
SCHEMBL18904519 0.76 CDC25B (0.46) ADRB2ADRB1ADRB3TSHRSMN1; SMN2
SCHEMBL17124659 0.74 TSHR (0.44) TSHRALDH1A1MAPTCYP3A4ELANE
SCHEMBL14701264 0.74 KMT2A (0.34) TSHRSMN1; SMN2CDC25BKDM4E
SCHEMBL18904507 0.73 CDC25B (0.36) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL8413374 0.73 TDP1 (0.54) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL16243602 0.72 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1CDC25BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040225-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-26 US disclosed
US-8999624-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-07 US disclosed
US-20150050601-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF GLOBALFOUNDRIES U.S. INC. 2015-02-19 US disclosed
US-8715907-B2 Developable bottom antireflective coating compositions for negative resists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-06 US disclosed
US-20130040238-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-14 US disclosed