SCHEMBL14701256

SCHEMBL14701256

C=Cc1ccc(N(c2ccccc2)c2ccc(/C=C(\C#N)C(=O)OCCOCCOC(=O)/C(C#N)=C/c3ccc(N(c4ccccc4)c4ccc(C=C)cc4)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.49
IDE P14735 1/20 0.45
MAPT P10636 5/20 0.45
ALDH1A1 P00352 5/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
APP P05067 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14701199 0.91 DNM1 (0.58) DNM1IDEMAPTALDH1A1MEN1
SCHEMBL15490835 0.89 DNM1 (0.47) DNM1IDEMAPTALDH1A1MEN1
SCHEMBL15521649 0.85 DNM1 (0.50) DNM1IDEMAPTALDH1A1MEN1
SCHEMBL15491106 0.85 DNM1 (0.50) DNM1IDEMAPTALDH1A1MEN1
SCHEMBL15373526 0.83 ALDH1A1 (0.56) DNM1MAPTALDH1A1MEN1KMT2A
SCHEMBL15371832 0.83 DNM1 (0.53) DNM1IDEMAPTALDH1A1MEN1
SCHEMBL15371833 0.82 ALDH1A1 (0.64) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL15491108 0.80 DNM1 (0.54) DNM1MAPTALDH1A1MEN1KMT2A
SCHEMBL16231340 0.80 MAPT (0.56) DNM1MAPTALDH1A1MEN1KMT2A
SCHEMBL15491151 0.80 IDE (0.46) IDEMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 DNM1 4420/4885IDE 3612/4885MAPT 458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.