SCHEMBL14701269

SCHEMBL14701269

C=CC(=O)OCc1ccc2c(c1)CC=C(O)C2

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.34
THRB P10828 3/20 0.32
MET P08581 1/20 0.32
HCAR2 Q8TDS4 4/20 0.32
CYP3A4 P08684 1/20 0.31
AKR1B10 O60218 2/20 0.30
AKR1B1 P15121 2/20 0.30
TTR P02766 1/20 0.30
RXRB P28702 1/20 0.30
CA12 O43570 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16743390 0.86 NAAA (0.30) NAAA
SCHEMBL14701268 0.82 CYP3A4 (0.36) NAAACYP3A4RXRB
SCHEMBL2604693 0.80 MAPT (0.39) NAAATHRBHCAR2CYP3A4
SCHEMBL2556244 0.73 HCAR2 (0.50) THRBHCAR2CYP3A4AKR1B10AKR1B1
SCHEMBL16125664 0.72 THRB (0.49) THRBHCAR2CYP3A4
SCHEMBL4578050 0.71 MEN1 (0.55) THRBMETHCAR2CYP3A4AKR1B10
SCHEMBL227301 0.70 HCAR2 (0.51) THRBHCAR2CYP3A4AKR1B10AKR1B1
SCHEMBL1898363 0.69 HCAR2 (0.48) THRBHCAR2AKR1B10AKR1B1TTR
SCHEMBL21913948 0.69 TSHR (0.46) THRBMETHCAR2CYP3A4AKR1B10
SCHEMBL12268165 0.68 HCAR2 (0.46) THRBMETHCAR2CYP3A4AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040225-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-26 US disclosed
US-8999624-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-07 US disclosed
US-20150050601-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF GLOBALFOUNDRIES U.S. INC. 2015-02-19 US disclosed
US-8715907-B2 Developable bottom antireflective coating compositions for negative resists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-06 US disclosed
US-20130040238-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-14 US disclosed