SCHEMBL14701302

SCHEMBL14701302

C=CC(=O)OCc1cccc2c(O)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
CYBB P04839 1/20 0.39
CDC25B P30305 2/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
TGM2 P21980 2/20 0.36
F13A1 P00488 1/20 0.36
TGM1 P22735 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 2/20 0.36
JAK2 O60674 1/20 0.36
USP2 O75604 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
EPHX1 P07099 1/20 0.35
TSHR P16473 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27421526 0.92 THRB (0.45) THRBTGM2F13A1TGM1MEN1
SCHEMBL24609573 0.91 THRB (0.43) THRBCDC25BESR1ESR2HSD17B10
SCHEMBL27586348 0.84 CYBB (0.50) THRBCYBBTSHRALDH1A1TP53
SCHEMBL960201 0.83 IDO1 (0.48) THRBCYBBHSD17B10TSHRALDH1A1
SCHEMBL2167443 0.83 MEN1 (0.51) THRBTGM2F13A1TGM1MEN1
SCHEMBL29484778 0.83 MEN1 (0.51) THRBTGM2F13A1TGM1MEN1
SCHEMBL29433901 0.81 MEP1B (0.44) THRBCYBBTGM2F13A1TGM1
SCHEMBL29503663 0.81 MEN1 (0.44) THRBTGM2F13A1TGM1MEN1
SCHEMBL29577996 0.79 THRB (0.53) THRBHSD17B10SMN1; SMN2TSHRALDH1A1
SCHEMBL10451653 0.79 THRB (0.53) THRBHSD17B10SMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040225-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-05-26 US disclosed
US-8999624-B2 Developable bottom antireflective coating composition and pattern forming method using thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-04-07 US disclosed
US-20150050601-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITION AND PATTERN FORMING METHOD USING THEREOF GLOBALFOUNDRIES U.S. INC. 2015-02-19 US disclosed
US-8715907-B2 Developable bottom antireflective coating compositions for negative resists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-06 US disclosed
US-20130040238-A1 DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-02-14 US disclosed