SCHEMBL27586348

SCHEMBL27586348

C=CC(=O)OCc1cccc(O)c1O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYBB P04839 1/20 0.50
IAPP P10997 4/20 0.44
THRB P10828 1/20 0.41
APP P05067 1/20 0.38
ALOX5 P09917 1/20 0.37
TSHR P16473 3/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
TP53 P04637 1/20 0.36
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL960201 0.86 IDO1 (0.48) CYBBTHRBTSHRALDH1A1CYP3A4
SCHEMBL14701302 0.84 THRB (0.40) CYBBTHRBTSHRALDH1A1CYP3A4
SCHEMBL29433901 0.84 MEP1B (0.44) CYBBTHRBTSHRALDH1A1CYP3A4
SCHEMBL961691 0.84 THRB (0.50) CYBBIAPPTHRBALOX5TSHR
SCHEMBL29577996 0.82 THRB (0.53) THRBTSHRALDH1A1CYP3A4TP53
SCHEMBL10451653 0.82 THRB (0.53) THRBTSHRALDH1A1CYP3A4TP53
SCHEMBL27421526 0.81 THRB (0.45) THRBTSHRALDH1A1CYP3A4TP53
SCHEMBL13822308 0.77 CYBB (0.54) CYBBIAPPALDH1A1
SCHEMBL9555275 0.76 THRB (0.47) THRBTSHRALDH1A1CYP3A4TP53
SCHEMBL7181027 0.76 THRB (0.47) THRBTSHRALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102591153-B Light-sensitive resin as well as preparation method and application thereof MIANYANG TRULY ELECTRONICS MFG LTD 2013-12-04 CN claimed
CN-1398362-A Antireflective coating compsns. SHIPLEY CO LLC (US) 2003-02-19 CN claimed
CN-104423700-B Window substrate and the touch panel with the window substrate 东友精细化工有限公司 2017-09-22 CN disclosed
CN-102591153-B Light-sensitive resin as well as preparation method and application thereof MIANYANG TRULY ELECTRONICS MFG LTD 2013-12-04 CN disclosed
CN-101017326-B Coating compositions for use with an overcoated photoresist ROHM & HAAS ELECT MAT 2011-10-12 CN disclosed
CN-101017326-A Coating compositions for use with an overcoated photoresist ROHM & HAAS ELECT MAT (US) 2007-08-15 CN disclosed
CN-1398362-A Antireflective coating compsns. SHIPLEY CO LLC (US) 2003-02-19 CN disclosed