Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.48 |
| ▸ | BACE1 | P56817 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701484 | 1.00 | CYP3A4 (0.77) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| (+/-)-Pentaacetylcatechin SCHEMBL719420 | 0.87 | ALDH1A1 (1.00) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| Epicatechin Pentaacetate SCHEMBL14691288 | 0.87 | ALDH1A1 (1.00) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| Catechin Pentaacetate SCHEMBL719419 | 0.87 | ALDH1A1 (1.00) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| (+/-)-Pentaacetylcatechin SCHEMBL14701425 | 0.87 | ALDH1A1 (1.00) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14701451 | 0.84 | BACE1 (0.65) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29682334 | 0.84 | BACE1 (0.65) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29105259 | 0.84 | BACE1 (0.65) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15653779 | 0.84 | MEN1 (0.78) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16150664 | 0.83 | CYP3A4 (0.55) | CYP3A4MAPK1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266699-A1 | Flavonoid compounds capable of modifying the dynamic and/or physical state of biological membranes and to stimulate the endogenous synthesis of stress proteins in eukaryotic cells, relative synthesis and their use | BRANE TECH S.R.L. (IT) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266699-A1 | Flavonoid compounds capable of modifying the dynamic and/or physical state of biological membranes and to stimulate the endogenous synthesis of stress proteins in eukaryotic cells, relative synthesis and their use | TFEB, HSF1, JUN | CYP3A4 1736/4885MAPK1 192/4885ALDH1A1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.