SCHEMBL17209482

SCHEMBL17209482

Brc1ccc2c(c1)C(c1cc(C3c4cc(Br)ccc4-c4ccc(Br)cc43)cc(C3c4cc(Br)ccc4-c4ccc(Br)cc43)c1)c1cc(Br)ccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.39
PTPRC P08575 1/20 0.34
KDM1A O60341 7/20 0.34
KDM1B Q8NB78 2/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
PGR P06401 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
MAPK1 P28482 1/20 0.33
BCL2 P10415 1/20 0.33
MCL1 Q07820 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16682952 0.86 PGR (0.36) S100A4KDM1AKDM1BNOS3NOS1
SCHEMBL12156932 0.85 HAO1 (0.41) S100A4PTPRCKDM1AKDM1BNOS3
SCHEMBL14701534 0.85 MEN1 (0.42) S100A4PTPRCKDM1APGRMEN1
SCHEMBL14212634 0.81 ALDH1A1 (0.44) S100A4PGRMEN1KMT2AMAPK1
SCHEMBL21174548 0.80 MEN1 (0.43) PTPRCKDM1AMEN1KMT2ACYP1A2
SCHEMBL20869346 0.80 MEN1 (0.43) PTPRCKDM1AMEN1KMT2ACYP1A2
SCHEMBL20615090 0.78 SLC6A2 (0.40) PTPRCPGRMEN1KMT2ACYP1A2
SCHEMBL1240051 0.75 S100A4 (0.42) S100A4PTPRCKDM1AKDM1BNOS3
SCHEMBL15164214 0.74 SPHK1 (0.40) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL17209529 0.73 LCK (0.36) S100A4PTPRCMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed