Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701569 | 1.00 | MMP1 (0.36) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL19852089 | 0.89 | SLC1A3 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL14701571 | 0.89 | SLC1A3 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL19851970 | 0.89 | SLC1A3 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL19328626 | 0.80 | MMP8 (0.36) | MMP8 | |
| SCHEMBL14701647 | 0.77 | MMP2 (0.33) | MMP2MMP9MMP8 | |
| SCHEMBL12120675 | 0.77 | — | — | |
| SCHEMBL19851978 | 0.76 | — | — | |
| SCHEMBL24140629 | 0.74 | MMP8 (0.36) | MMP8 | |
| SCHEMBL12120664 | 0.74 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-05-05 | — | — | US | disclosed |
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-02-08 | — | — | US | disclosed |
| WO-2013023003-A1 | BIOACTIVE AMPHIPHILIC POLYMER STABILIZED NANOPARTICLES WITH ENHANCED STABILITY AND ACTIVITY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037840-A1 | THERMOCLEAVABLE FRICTION MODIFIERS AND METHODS THEREOF | F12, F5, F3 | MMP1 683/4885MMP2 2609/4885MMP3 1101/4885 |
| US-10640725-B2 | Thermocleavable friction modifiers and methods thereof | F12, F5, F3 | MMP1 683/4885MMP2 2609/4885MMP3 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.