Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701568 | 1.00 | MMP1 (0.36) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL19852089 | 0.89 | SLC1A3 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL14701571 | 0.89 | SLC1A3 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL19851970 | 0.89 | SLC1A3 (0.34) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL19328626 | 0.80 | MMP8 (0.36) | MMP8 | |
| SCHEMBL14701647 | 0.77 | MMP2 (0.33) | MMP2MMP9MMP8 | |
| SCHEMBL12120675 | 0.77 | — | — | |
| SCHEMBL19851978 | 0.76 | — | — | |
| SCHEMBL24140629 | 0.74 | MMP8 (0.36) | MMP8 | |
| SCHEMBL12120664 | 0.74 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023003-A1 | BIOACTIVE AMPHIPHILIC POLYMER STABILIZED NANOPARTICLES WITH ENHANCED STABILITY AND ACTIVITY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-02-14 | — | — | WO | disclosed |