Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25662434 | 0.93 | TSHR (0.59) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL8750481 | 0.82 | TSHR (0.64) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL28734969 | 0.80 | TSHR (0.68) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL117710 | 0.80 | TSHR (1.00) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL8094364 | 0.80 | TSHR (0.45) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL11270656 | 0.78 | TSHR (0.59) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL2491929 | 0.78 | TSHR (0.58) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL8089660 | 0.77 | ALDH1A1 (0.52) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL29262161 | 0.77 | L3MBTL1 (0.57) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL28650496 | 0.77 | L3MBTL1 (0.57) | TSHRMAPK1ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909379-B | Preparation method of thioether polymer | 江汉大学 | 2022-09-20 | — | — | CN | claimed |
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-112250866-B | Preparation method of free radical type photocuring resin with thioether as main chain | 江汉大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-111909379-B | Preparation method of thioether polymer | 江汉大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-110551146-B | Continuous preparation method of benzyl zinc halide and derivatives thereof | 凯莱英医药集团（天津）股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-112250866-A | Preparation method of free radical type photocuring resin with thioether as main chain | 江汉大学 | 2021-01-22 | — | — | CN | disclosed |
| CN-111909379-A | Preparation method of thioether polymer | 江汉大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-110551146-A | Continuous preparation method of benzyl zinc halide and derivatives thereof | ASYMCHEM LAB TIANJIN CO LTD | 2019-12-10 | — | — | CN | disclosed |
| CN-109111463-A | The manufacturing method of aromatic compound | DIC株式会社 | 2019-01-01 | — | — | CN | disclosed |
| US-20120059137-A1 | MONODISPERSE CHLOROMETHYLSTYRENE POLYMER AND PRODUCING METHOD THEREOF | AGC SEIMI CHEMICAL CO., LTD. (JP) | 2012-03-08 | — | — | US | disclosed |
| EP-0849253-B1 | Process for producing benzoyl chlorides | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-05-16 | — | — | EP | disclosed |
| EP-1053990-A2 | A method of producing an aromatic ketone and an aromatic ketone composition containing it | TORAY INDUSTRIES, INC. (JP) | 2000-11-22 | — | — | EP | disclosed |
| US-5872291-A | Process for producing benzoyl chlorides | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0849253-A1 | Process for producing benzoyl chlorides | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-06-24 | — | — | EP | disclosed |
| EP-0150169-B1 | A PROCESS FOR PREPARING SUBSTITUTED BENZOTRICHLORIDE COMPOUNDS | Monsanto Company (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4593144-A | REACTING SUBSTITUTED BENZAL CHLORIDES WITH PRECHLOROALKANE IN PRESENCE OF BASE AND PHASE TRANSFER CATALYST | MONSANTO COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0150169-A2 | A process for preparing substituted benzotrichloride compounds | Monsanto Company (US) | 1985-07-31 | — | — | EP | disclosed |