SCHEMBL8094364

SCHEMBL8094364

CCCc1ccc(C(Cl)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
LPL P06858 2/20 0.45
LIPG Q9Y5X9 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPK1 P28482 1/20 0.45
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CA2 P00918 1/20 0.42
ACACB O00763 2/20 0.40
MGLL Q99685 1/20 0.39
PLK1 P53350 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
THRB P10828 1/20 0.38
HTR2A P28223 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089660 0.86 ALDH1A1 (0.52) TSHRLPLLIPGL3MBTL1MAPK1
SCHEMBL14396739 0.84 L3MBTL1 (0.43) TSHRLPLLIPGL3MBTL1MAPK1
SCHEMBL11468439 0.83 HTR2A (0.57) TSHRLPLLIPGMGLLKDM4E
SCHEMBL2491588 0.80 LPL (0.48) TSHRLPLLIPGL3MBTL1MAPK1
SCHEMBL147032 0.80 TSHR (0.67) TSHRLPLLIPGL3MBTL1MAPK1
SCHEMBL142480 0.79 LPL (0.62) LPLLIPGL3MBTL1CA2MGLL
SCHEMBL597719 0.78 IDO1 (0.50) LPLLIPGL3MBTL1CA2ACACB
SCHEMBL9621041 0.78 LPL (0.46) LPLLIPGL3MBTL1CA2ACACB
SCHEMBL8097075 0.76 LPL (0.45) LPLLIPGL3MBTL1CA2ACACB
SCHEMBL9152292 0.76 LPL (0.45) LPLLIPGL3MBTL1CA2ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111463-A The manufacturing method of aromatic compound DIC株式会社 2019-01-01 CN disclosed
EP-1053990-A2 A method of producing an aromatic ketone and an aromatic ketone composition containing it TORAY INDUSTRIES, INC. (JP) 2000-11-22 EP disclosed