Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14687788 | 0.87 | KDM4E (0.43) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL21878516 | 0.85 | RAB9A (0.42) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL11563719 | 0.84 | KDM4E (0.41) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL14687435 | 0.84 | KDM4E (0.42) | RAB9AKDM4EALDH1A1HPGDP2RX3 | |
| SCHEMBL20502950 | 0.83 | RAB9A (0.49) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL28356202 | 0.82 | TARBP2 (0.51) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL14702238 | 0.82 | RAB9A (0.46) | RAB9AKDM4EALDH1A1HPGDP2RX3 | |
| SCHEMBL28352443 | 0.82 | RAB9A (0.40) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL21878515 | 0.81 | RAB9A (0.47) | RAB9AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL20502879 | 0.81 | KDM4E (0.41) | RAB9AKDM4EALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770209-B | Novel 5-hydroxypyridine compounds useful as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2023-06-30 | — | — | CN | disclosed |
| US-11319289-B2 | 5-hydroxy pyridine-based compound for use as P2X1 and P2X3 receptor antagonist and pharmaceutical composition comprising same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-05-03 | — | — | US | disclosed |
| US-20200131131-A1 | NOVEL 5-HYDROXY PYRIDINE-BASED COMPOUND FOR USE AS P2X1 AND P2X3 RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-04-30 | — | — | US | disclosed |
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | disclosed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319289-B2 | 5-hydroxy pyridine-based compound for use as P2X1 and P2X3 receptor antagonist and pharmaceutical composition comprising same | P2RX5, P2RX3, P2RX1 | RAB9A 3026/4885KDM4E 1863/4885ALDH1A1 1351/4885 |
| US-20200131131-A1 | NOVEL 5-HYDROXY PYRIDINE-BASED COMPOUND FOR USE AS P2X1 AND P2X3 RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | P2RX5, P2RX3, P2RX1 | RAB9A 3077/4885KDM4E 1918/4885ALDH1A1 1488/4885 |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | P2RX3, P2RX1, P2RX2 | RAB9A 2696/4885KDM4E 3029/4885ALDH1A1 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.