Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 2/20 | 0.51 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14704236 | 0.82 | RAB9A (0.45) | POLBKMT2AGLAMAPTRAB9A | |
| SCHEMBL3769312 | 0.80 | P2RX3 (0.50) | TARBP2PDCD4RXFP1POLBKMT2A | |
| SCHEMBL5192166 | 0.80 | TARBP2 (0.75) | TARBP2PDCD4POLBKMT2AMAPT | |
| SCHEMBL14687788 | 0.79 | KDM4E (0.43) | POLBKMT2AMAPTRAB9ANPC1 | |
| SCHEMBL21878516 | 0.77 | RAB9A (0.42) | POLBKMT2AMAPTRAB9ANPC1 | |
| SCHEMBL29025968 | 0.76 | TARBP2 (0.50) | TARBP2PDCD4POLBGLAMAPT | |
| SCHEMBL20502950 | 0.75 | RAB9A (0.49) | KMT2AMAPTRAB9ANPC1LMNA | |
| SCHEMBL14687895 | 0.75 | CYP4A11 (0.46) | KMT2AMAPTRAB9ANPC1GAA | |
| SCHEMBL28352443 | 0.74 | RAB9A (0.40) | POLBKMT2AMAPTRAB9ANPC1 | |
| SCHEMBL20502879 | 0.73 | KDM4E (0.41) | POLBKMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770209-B | Novel 5-hydroxypyridine compounds useful as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2023-06-30 | — | — | CN | disclosed |
| CN-110770209-A | Novel 5-hydroxypyridines as P2X1 and P2X3 receptor antagonists and pharmaceutical compositions containing the same | 光州科学技术院 | 2020-02-07 | — | — | CN | disclosed |