Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.57 |
| ▸ | FNTB | P49356 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135856 | 0.91 | MEN1 (0.64) | MEN1KMT2ASOAT2SOAT1HDAC3 | |
| SCHEMBL20183907 | 0.85 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2RAB9APOLB | |
| SCHEMBL9667027 | 0.84 | SOAT2 (0.72) | SOAT2SOAT1HDAC3EGFRHDAC4 | |
| SCHEMBL9664918 | 0.84 | SOAT2 (0.72) | SOAT2SOAT1HDAC3EGFRHDAC4 | |
| SCHEMBL9664783 | 0.84 | SOAT2 (0.72) | SOAT2SOAT1HDAC3EGFRHDAC4 | |
| SCHEMBL9666631 | 0.84 | SOAT2 (0.72) | SOAT2SOAT1HDAC3EGFRHDAC4 | |
| SCHEMBL9664865 | 0.84 | SOAT2 (0.72) | SOAT2SOAT1HDAC3EGFRHDAC4 | |
| SCHEMBL9664720 | 0.82 | SOAT2 (0.69) | SOAT2SOAT1HDAC3EGFRHDAC4 | |
| SCHEMBL8088822 | 0.79 | MEN1 (0.72) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL11901010 | 0.79 | LMNA (0.69) | MEN1KMT2ASOAT2SOAT1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040952-A1 | INFLUENZA VIRUS INHIBITORS THAT DISRUPT NUCLEOPROTEIN TRIMERIZATION | ACADEMIA SINICA (TW) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040952-A1 | INFLUENZA VIRUS INHIBITORS THAT DISRUPT NUCLEOPROTEIN TRIMERIZATION | NPM1, NAP1L1, NAP1L4 | FNTA 2358/4885FNTB 1765/4885RCE1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.