Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105734 | 0.94 | CYP2C9 (0.42) | TP53L3MBTL1CYP2C9ALDH1A1LMNA | |
| SCHEMBL14706832 | 0.78 | SNCA (0.48) | TP53L3MBTL1ALDH1A1LMNASNCA | |
| SCHEMBL1105806 | 0.78 | SNCA (0.48) | TP53L3MBTL1ALDH1A1LMNASNCA | |
| SCHEMBL14708697 | 0.77 | KMT2A (0.43) | TP53L3MBTL1CYP2C9ALDH1A1LMNA | |
| SCHEMBL14747438 | 0.72 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL19107139 | 0.70 | HDAC1 (0.36) | TP53L3MBTL1ALDH1A1LMNAMEN1 | |
| SCHEMBL1105637 | 0.70 | BCHE (0.48) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14747435 | 0.69 | LMNA (0.38) | TP53CYP2C9ALDH1A1LMNAMEN1 | |
| SCHEMBL1105635 | 0.67 | MAPT (0.36) | TP53ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL14747436 | 0.67 | CHRM2 (0.56) | TP53L3MBTL1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |