SCHEMBL14708697

SCHEMBL14708697

O=C(O)CCCCCN1CCCc2cc(/C=C/c3nc4ccc(S(=O)(=O)N5CCCCC5)cc4s3)ccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.43
▸ MEN1 O00255 5/20 0.43
▸ HTT P42858 4/20 0.43
▸ TP53 P04637 3/20 0.43
▸ LMNA P02545 3/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ CYP2C9 P11712 1/20 0.42
▸ ALDH1A1 P00352 9/20 0.42
▸ MAPT P10636 4/20 0.42
▸ HPGD P15428 3/20 0.42
▸ VDR P11473 1/20 0.42
▸ GFER P55789 1/20 0.42
▸ GPR55 Q9Y2T6 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ HSD17B10 Q99714 3/20 0.40
▸ USP2 O75604 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ MAPK1 P28482 2/20 0.39
▸ GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105734 0.83 CYP2C9 (0.42) KMT2AMEN1HTTTP53LMNA
SCHEMBL14747445 0.77 TP53 (0.42) KMT2AMEN1HTTTP53LMNA
SCHEMBL14708648 0.76 ALDH1A1 (0.54) KMT2AMEN1HTTTP53LMNA
SCHEMBL15827270 0.73 MEN1 (0.41) KMT2AMEN1HTTTP53LMNA
SCHEMBL1105690 0.71 MEN1 (0.53) KMT2AMEN1HTTTP53LMNA
SCHEMBL15827289 0.67 LMNA (0.47) KMT2AMEN1HTTTP53LMNA
SCHEMBL12999117 0.67 MAPT (0.47) KMT2AMEN1HTTL3MBTL1ALDH1A1
SCHEMBL19871386 0.65 HSD17B10 (0.53) KMT2AMEN1HTTTP53LMNA
SCHEMBL21248477 0.63 MEN1 (0.58) KMT2AMEN1HTTTP53LMNA
SCHEMBL1105634 0.63 MEN1 (0.65) KMT2AMEN1L3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8759526-B2 Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules ENZO LIFE SCIENCES, INC. (US) 2014-06-24 — — US disclosed
US-20130045480-A1 Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2013-02-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045480-A1 Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules ANXA5, DCLRE1B, ANXA4 KMT2A 4679/4885MEN1 4221/4885HTT 1776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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