Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.60 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GNG2 | P59768 | 1/20 | 0.39 |
| ▸ | GNB1 | P62873 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1469054 | 0.91 | GSTP1 (0.49) | GSTP1FTOMAPTMEN1HTT | |
| SCHEMBL7973211 | 0.87 | GSTP1 (0.59) | GSTP1FTOMAPTMEN1HTT | |
| SCHEMBL329252 | 0.84 | FTO (0.67) | GSTP1FTOMAPTMEN1HTT | |
| SCHEMBL9538912 | 0.83 | FTO (0.69) | GSTP1FTOMAPTMEN1HTT | |
| Dichlorofluorescein SCHEMBL29364373 | 0.82 | MAPT (0.64) | FTOMAPTMEN1HTTKMT2A | |
| Dichlorofluorescein SCHEMBL30606648 | 0.82 | MAPT (0.64) | FTOMAPTMEN1HTTKMT2A | |
| Dichlorofluorescein SCHEMBL157703 | 0.82 | MAPT (0.64) | FTOMAPTMEN1HTTKMT2A | |
| Dichlorofluorescein SCHEMBL25207800 | 0.81 | MAPT (0.63) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL1299465 | 0.81 | FTO (0.47) | GSTP1FTOMAPTMEN1HTT | |
| SCHEMBL29371871 | 0.81 | FTO (0.47) | GSTP1FTOMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110070166-A1 | REDUCED DYE PROBES FOR THE DETECTION OF RADICAL OXYGEN SPECIES | GEORGIA TECH RESEARCH CORPORATION | 2011-03-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110070166-A1 | REDUCED DYE PROBES FOR THE DETECTION OF RADICAL OXYGEN SPECIES | ROS1, GPX4, DHRS9 | GSTP1 431/4885FTO 2384/4885MAPT 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.