Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744850 | 0.84 | OPRM1 (0.56) | OPRM1HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL14710297 | 0.84 | HSD11B1 (0.40) | OPRM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11467518 | 0.83 | OPRM1 (0.46) | OPRM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15548256 | 0.83 | KDM4E (0.46) | OPRM1LMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL11462401 | 0.82 | LMNA (0.48) | OPRM1HDAC1LMNAMEN1KMT2A | |
| SCHEMBL14790321 | 0.82 | OPRM1 (0.42) | OPRM1HDAC1LMNAMEN1KMT2A | |
| SCHEMBL15912440 | 0.82 | OPRM1 (0.42) | OPRM1HDAC1LMNAMEN1KMT2A | |
| SCHEMBL14710263 | 0.80 | HRH3 (0.45) | OPRM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14710667 | 0.78 | OPRM1 (0.40) | OPRM1HDAC1LMNAMEN1KMT2A | |
| SCHEMBL8584110 | 0.77 | ALDH1A1 (0.51) | HDAC1LMNAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |