SCHEMBL1471236

SCHEMBL1471236

NS(=O)(=O)c1ccccc1I

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 16/20 0.56
CA1 P00915 12/20 0.56
CA9 Q16790 11/20 0.56
CA12 O43570 6/20 0.56
CA6 P23280 4/20 0.56
CA5A P35218 4/20 0.56
CA7 P43166 4/20 0.56
CA4 P22748 3/20 0.56
CA5B Q9Y2D0 3/20 0.56
CA14 Q9ULX7 2/20 0.56
CYP2C9 P11712 1/20 0.56
CA3 P07451 1/20 0.44
PLA2G7 Q13093 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
LDHA P00338 1/20 0.43
CDK2 P24941 1/20 0.43
GAA P10253 1/20 0.41
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29469861 1.00 CA2 (0.56) CA2CA1CA9CA12CA6
SCHEMBL4812059 0.81 CA2 (0.47) CA2CA1CA9CA12CA6
SCHEMBL202947 0.81 CA2 (0.70) CA2CA1CA9CA12CA6
SCHEMBL1682100 0.79 GAA (0.50) CA2CA1CA9CA12CA6
SCHEMBL10750170 0.78 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL10750176 0.78 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL10749655 0.78 CA2 (0.67) CA2CA1CA9CA12CA6
SCHEMBL28787703 0.78 CDK2 (0.62) CA2CA1CA9CA12CA6
SCHEMBL19309899 0.78 CA2 (0.44) CA2CA1CA9CA12CA6
SCHEMBL9745397 0.77 GAA (0.37) CA2CA1CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101932244-A Salts of 2-lodo-n-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl] benzol sulphonamide, method for its manufacture and its application as herbicide and plant growth regulator BAYER CROPSCIENCE AG 2010-12-29 CN claimed
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYERCROPSCIENCE AG (DE) 2010-11-11 US claimed
EP-2052604-A1 Salts of 2-lodo-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl] benzol sulphonamide, method for its manufacture and its application as herbicide and plant growth regulator Bayer CropScience AG (DE) 2009-04-29 EP claimed
EP-0644188-A1 Process for the preparation of sulfur derivatives of imidazole and intermediates obtained ROUSSEL UCLAF (FR) 1995-03-22 EP claimed
CN-1100415-A New preparation process for sulphurated derivatives of imidazole and the new intermediates obtained ROUSSEL UCLAF (FR) 1995-03-22 CN claimed
WO-2026104681-A1 NEW SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed
WO-2026104679-A1 NOVEL SULFONAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-05-21 WO disclosed
US-20240279207-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BAYER AKTIENGESELLSCHAFT (DE) 2024-08-22 US disclosed
EP-4229048-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER The Broad Institute, Inc. (US) 2023-08-23 EP disclosed
WO-2022081807-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER THE BROAD INSTITUTE, INC. (US) 2022-04-21 WO disclosed
WO-2021081677-A1 CHIRAL GUANIDINES, SALTS THEREOF, METHODS OF MAKING CHIRAL GUANIDINES AND SALTS THEREOF, AND USES OF CHIRAL GUANIDINES AND SALTS THEREOF IN THE PREPARATION OF ENANTIOMERICALLY PURE AMINO ACIDS FU RUI (CA) 2021-05-06 WO disclosed
CN-107033093-B N- substituted sulphonamide compound and the preparation method and application thereof 浙江工业大学 2019-09-03 CN disclosed
EP-0644188-A1 Process for the preparation of sulfur derivatives of imidazole and intermediates obtained ROUSSEL UCLAF (FR) 1995-03-22 EP disclosed
US-5391732-A Cardiotonic agents, hypotensive agents, antispasmodic agents ROUSSEL-UCLAF (FR) 1995-02-21 US disclosed
CN-1096511-A The preparation method of biphenyl derivatives HOECHST AG (DE) 1994-12-21 CN disclosed
US-5248693-A Antiallergens, antiinflammatory agents CIBA-GEIGY CORPORATION (US) 1993-09-28 US disclosed
EP-0539329-A1 Acetenyl compounds useful as leukotrien antagonists CIBA-GEIGY AG (CH) 1993-04-28 EP disclosed
US-4727186-A PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1988-02-23 US disclosed
US-4594097-A Herbicide CIBA-GEIGY CORPORATION (US) 1986-06-10 US disclosed
US-4537618-A PRE-AND POST-EMERGENCE HIRBICIDE CIBA GEIGY CORPORATION (US) 1985-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS MYB, INMT, AS3MT CA2 333/4885CA1 2602/4885CA9 1497/4885
US-20240279207-A1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER KAT6A, KAT6B, KAT2A CA2 2865/4885CA1 1714/4885CA9 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.