SCHEMBL14714513

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14715042	0.83	LMNA (0.54)	ROCK2SMN1; SMN2
	SCHEMBL14714737	0.83	KLKB1 (0.51)	MEN1KMT2AROCK2KLKB1KDM1A
	SCHEMBL14715281	0.83	HRH3 (0.42)	HRH3KMT2APPARGROCK2KLKB1
	SCHEMBL14714539	0.83	HPGDS (0.42)	HRH3HSD17B10PPARGROCK2ALDH1A1
	SCHEMBL14715019	0.83	HRH3 (0.42)	HRH3HSD17B10EGLN2PPARGALDH1A1
	SCHEMBL14715228	0.81	HRH3 (0.41)	HRH3PPARGROCK2SMN1; SMN2GAA
	SCHEMBL14715195	0.81	TSHR (0.57)	MEN1KMT2AROCK2SMN1; SMN2HDAC1
	SCHEMBL14715049	0.81	PPARG (0.51)	HRH3PPARGGAA
	SCHEMBL14715425	0.80	PPARG (0.50)	HRH3MEN1KMT2APPARG
	SCHEMBL14714981	0.79	ANPEP (0.49)	HRH3PPARGGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.