SCHEMBL14714853

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14714600	0.86	NPC1 (0.46)	RAB9ACTDSP1NPC1KMT2AMAPT
	SCHEMBL14714633	0.82	PLK1 (0.40)	RAB9AMAPTHTTKDM4EGAA
	SCHEMBL14714456	0.80	NPC1 (0.56)	RAB9ACTDSP1NPC1KMT2AMAPT
	SCHEMBL10438916	0.77	POLB (0.50)	RAB9ANPC1MAPTKDM4EGAA
	SCHEMBL14724517	0.77	RAB9A (0.49)	RAB9ACTDSP1NPC1KMT2AMAPT
	SCHEMBL6416083	0.76	NPC1 (0.60)	RAB9ACTDSP1NPC1KMT2AMAPT
	SCHEMBL2026287	0.74	NPC1 (0.67)	RAB9ACTDSP1NPC1KMT2AMAPT
	Hydrochloric Acid SCHEMBL16600494	0.72	NPC1 (0.64)	RAB9ACTDSP1NPC1KMT2AMAPT
	SCHEMBL2119968	0.72	OGG1 (0.43)	RAB9ACTDSP1NPC1KMT2AMAPT
	SCHEMBL14724509	0.71	MAPT (0.43)	RAB9ACTDSP1NPC1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.