SCHEMBL14714633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14714853	0.82	RAB9A (0.46)	TRPV1HTTSMN1; SMN2MAPTRAB9A
	SCHEMBL21094187	0.77	TAS1R3 (0.41)	PLK1TRPV1HPGDMAPTTPMT
	SCHEMBL16998400	0.77	NPSR1 (0.33)	ALDH1A1
	SCHEMBL14724481	0.76	MAPK1 (0.41)	TSHRSMN1; SMN2MAPTRAB9AGAA
	SCHEMBL14714321	0.75	NOTUM (0.35)	—
	SCHEMBL8920815	0.75	LMNA (0.50)	TRPV1HTTSMN1; SMN2MAPTTPMT
	SCHEMBL17450277	0.73	GSTP1 (0.40)	HPGDTSHRSMN1; SMN2RAB9AALDH1A1
	SCHEMBL2144483	0.72	HDAC8 (0.64)	PLK1TRPV1HPGDTSHRHTT
	SCHEMBL2119968	0.71	OGG1 (0.43)	HPGDSMN1; SMN2HDAC2MAPTRAB9A
	SCHEMBL10438916	0.70	POLB (0.50)	TSHRSMN1; SMN2HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.