SCHEMBL147151

SCHEMBL147151

Cc1ccc(-c2ccccc2)s1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.48
HSD17B2 P37059 2/20 0.48
CYP2E1 P05181 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2A6 P11509 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2B6 P20813 1/20 0.48
CYP2C19 P33261 1/20 0.48
RAB9A P51151 3/20 0.46
NPC1 O15118 3/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
MAPK1 P28482 1/20 0.46
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10472380 0.95 HSD17B1 (0.50) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
SCHEMBL16706001 0.95 HSD17B1 (0.50) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
SCHEMBL13885536 0.95 RAB9A (0.52) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
Boric Acid SCHEMBL31280988 0.91 HSD17B1 (0.47) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
SCHEMBL23555791 0.89 HSD17B1 (0.50) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
SCHEMBL9927249 0.87 APP (0.48) HSD17B1HSD17B2RAB9ANPC1ALDH1A1
SCHEMBL13125887 0.84 APP (0.50) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
SCHEMBL13125897 0.84 APP (0.50) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
SCHEMBL13125875 0.84 APP (0.50) HSD17B1HSD17B2CYP2E1CYP3A4CYP2A6
SCHEMBL10300218 0.84 APP (0.46) HSD17B1HSD17B2RAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101029-A Photochromic diaryl ethylene compound and preparation method and application thereof 济宁医学院 2024-12-10 CN claimed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO claimed
CN-119101029-B Photochromic diaryl ethylene compound and preparation method and application thereof 济宁医学院 2025-06-13 CN disclosed
CN-119751410-A Method for thoroughly reducing aromatic oxide 郑州大学 2025-04-04 CN disclosed
CN-119101029-A Photochromic diaryl ethylene compound and preparation method and application thereof 济宁医学院 2024-12-10 CN disclosed
EP-4395521-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE COMPRISING THE CONDENSED CYCLIC COMPOUND, AND ELECTRONIC APPARATUS COMPRISING THE LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
EP-4389738-A1 SOS1 INHIBITOR AND USE THEREOF Kanaph Therapeutics Inc. (KR) 2024-06-26 EP disclosed
CN-118063461-A Red light/near infrared photochromic molecule, preparation method and application thereof 华东理工大学 2024-05-24 CN disclosed
WO-2024091882-A1 SMALL MOLECULE DIRECT INHIBITORS OF KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-05-02 WO disclosed
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
US-5977062-A ACTIVE AGAINST ANTIBIOTIC RESISTANT BACTERIA ELI LILLY AND COMPANY (US) 1999-11-02 US disclosed
US-5840684-A Glycopeptide antibiotic derivatives ELI LILLY AND COMPANY (US) 1998-11-24 US disclosed
EP-0420397-B1 Fulgimide derivatives WAKO PURE CHEM IND LTD (JP) 1995-11-29 EP disclosed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO disclosed
US-5359085-A Exhibits photochromic properties WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1994-10-25 US disclosed
EP-0420397-A1 Fulgimide derivatives WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1991-04-03 EP disclosed
EP-0032432-B1 PROSTANOID COMPOUNDS AND THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS GLAXO GROUP LIMITED (GB) 1985-07-24 EP disclosed
US-4438111-A PROSTAGLANDINS, ANTICOAGULANTS, ANTIASTHMA GLAXO GROUP LIMITED (GB) 1984-03-20 US disclosed
EP-0032432-A1 Prostanoid compounds and their preparation and pharmaceutical formulations GLAXO GROUP LIMITED (GB) 1981-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917913-B2 Substituted oxepines OXGR1, OXTR, OCIAD2 HSD17B1 4820/4885HSD17B2 4571/4885CYP2E1 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.