Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715003 | 0.81 | LMNA (0.39) | LMNASMN1; SMN2TK1SLC29A1TYMS | |
| SCHEMBL14946758 | 0.78 | TK1 (0.51) | LMNASMN1; SMN2TK1SLC29A1ALOX12 | |
| SCHEMBL20953781 | 0.78 | TK1 (0.51) | LMNASMN1; SMN2TK1SLC29A1ALOX12 | |
| SCHEMBL14714996 | 0.78 | TK1 (0.46) | LMNASMN1; SMN2TK1SLC29A1ALOX12 | |
| SCHEMBL2494647 | 0.78 | TK1 (0.51) | LMNASMN1; SMN2TK1SLC29A1ALOX12 | |
| SCHEMBL13488841 | 0.78 | TK1 (0.51) | LMNASMN1; SMN2TK1SLC29A1ALOX12 | |
| SCHEMBL14946754 | 0.78 | TK1 (0.46) | LMNASMN1; SMN2TK1SLC29A1ALOX12 | |
| SCHEMBL14715186 | 0.77 | LMNA (0.36) | LMNASMN1; SMN2TK1SLC29A1TYMS | |
| SCHEMBL2495045 | 0.76 | SLC29A1 (0.45) | LMNASMN1; SMN2TK1SLC29A1TYMS | |
| SCHEMBL14944711 | 0.76 | SLC29A1 (0.45) | LMNASMN1; SMN2TK1SLC29A1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9285319-B2 | Nucleic acid base analogs with quenching and fluorescent activities and applications thereof | RIKEN (JP) | 2016-03-15 | — | — | US | disclosed |
| US-20130122506-A1 | NUCLEIC ACID BASE ANALOGS WITH QUENCHING AND FLUORESCENT ACTIVITIES AND APPLICATIONS THEREOF | TAGCYX BIOTECHNOLOGIES C/O RIKEN (JP) | 2013-05-16 | — | — | US | disclosed |
| EP-2562255-A1 | NUCLEIC ACID BASE ANALOG WITH QUENCHING CHARACTERISTICS AND FLUORESCENCE AND APPLICATION THEREOF | Riken (JP) | 2013-02-27 | — | — | EP | disclosed |