Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CCNH | P51946 | 1/20 | 0.31 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471527 | 0.74 | HTR1A (0.75) | HTR1ALMNA | |
| SCHEMBL1471422 | 0.72 | PRMT6 (0.53) | ALDH1A1HTT | |
| SCHEMBL1471374 | 0.69 | HTR1A (0.38) | HTR1A | |
| SCHEMBL1471240 | 0.68 | RAB9A (0.47) | HTR1AALDH1A1LMNAHTT | |
| SCHEMBL1471413 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL1473277 | 0.64 | HTR1A (0.52) | HTR1A | |
| SCHEMBL6558765 | 0.63 | HTR2C (0.45) | LMNAHTT | |
| SCHEMBL4175928 | 0.63 | SMN1; SMN2 (0.49) | L3MBTL1ALDH1A1HTT | |
| SCHEMBL10047122 | 0.63 | L3MBTL1 (0.49) | L3MBTL1LMNAHTTSIGMAR1 | |
| SCHEMBL186274 | 0.62 | NOS1 (0.52) | HTR1AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | disclosed |