SCHEMBL1471533

SCHEMBL1471533

c1ccc(-c2cnc(-c3ccccc3-c3ncc(-c4ccccc4)o3)o2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.77
NPC1 O15118 5/20 0.77
ATM Q13315 1/20 0.77
ALOX15 P16050 1/20 0.74
TSHR P16473 1/20 0.74
CASP1 P29466 1/20 0.74
KMT2A Q03164 3/20 0.62
KDM4E B2RXH2 3/20 0.62
ALDH1A1 P00352 3/20 0.62
HPGD P15428 3/20 0.62
HSD17B10 Q99714 3/20 0.62
MEN1 O00255 2/20 0.62
MITF O75030 1/20 0.62
CREBBP Q92793 2/20 0.59
PTPN1 P18031 6/20 0.58
GAA P10253 3/20 0.58
TP53 P04637 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
LMNA P02545 1/20 0.54
CYP1A2 P05177 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3295181 0.96 RAB9A (0.72) RAB9ANPC1ATMALOX15TSHR
SCHEMBL4342614 0.88 ALOX15 (0.69) RAB9ANPC1ATMALOX15TSHR
SCHEMBL5701207 0.88 RAB9A (0.62) RAB9ANPC1ATMALOX15TSHR
SCHEMBL3936954 0.87 RAB9A (0.66) RAB9ANPC1ATMALOX15TSHR
SCHEMBL1208170 0.87 RAB9A (0.66) RAB9ANPC1ATMALOX15TSHR
SCHEMBL4879849 0.87 RAB9A (0.66) RAB9ANPC1ATMALOX15TSHR
SCHEMBL12794313 0.87 RAB9A (0.66) RAB9ANPC1ATMALOX15TSHR
SCHEMBL2680743 0.87 RAB9A (1.00) RAB9ANPC1ATMALOX15TSHR
SCHEMBL10495074 0.87 RAB9A (0.66) RAB9ANPC1ATMALOX15TSHR
SCHEMBL14133170 0.87 RAB9A (0.66) RAB9ANPC1ATMALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106008769-B The preparation method and application of gel for the verification of radiotherapy 3-dimensional dose 苏州大学 2018-11-02 CN claimed
US-20090130650-A1 Methods for the production of highly sensitive and specific cell surface probes TAN WEIHONG 2009-05-21 US claimed
US-20080272338-A1 DYE LOADED ZEOLITE MATERIAL UNIVERSITAET BERN (CH) 2008-11-06 US claimed
US-7372012-B2 Dye loaded zeolite material containing devices UNIVERSITAET BERN (CH) 2008-05-13 US claimed
WO-2007142713-A2 METHODS FOR THE PRODUCTION OF HIGHLY SENSITIVE AND SPECIFIC CELL SURFACE PROBES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-12-13 WO claimed
WO-2007075456-A2 COLORIMETRIC LIGHT SWITCHING PROBE FOR ULTRASENSITIVE DETECTION OF TARGET COMPOUNDS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-07-05 WO claimed
EP-1335879-B1 DYE LOADED ZEOLITE MATERIAL UNIV BERN (CH) 2007-01-03 EP claimed
US-20060001004-A1 Dye loaded zeolite material containing devices UNIVERSITAET BERN (CH) 2006-01-05 US claimed
US-6932919-B2 Dye loaded zeolite material UNIVERSITAET BERN (CH) 2005-08-23 US claimed
US-20040026662-A1 Dye loaded zeolite material UNIVERSITAET BERN (CH) 2004-02-12 US claimed
EP-1335879-A1 DYE LOADED ZEOLITE MATERIAL Universitaet Bern (CH) 2003-08-20 EP claimed
US-6447724-B1 DNA sequencing using multiple fluorescent labels being distinguishable by their decay times CALIPER TECHNOLOGIES CORP. 2002-09-10 US claimed
WO-2002036490-A1 DYE LOADED ZEOLITE MATERIAL UNIVERSITAET BERN (CH) 2002-05-10 WO claimed
EP-0484113-B1 Liquid/vapor optical modulator DU PONT (US) 1995-12-27 EP claimed
US-5193024-A Forming bubbles in a dye solution within a cell and focusing a beam from a laser, vaporization solvent and illumination of solution E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-09 US claimed
EP-0484113-A1 Liquid/vapor optical modulator E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-06 EP claimed
US-4819658-A Method and apparatus for measuring the temperature profile of a surface AMERICAN TELEPHONE AND TELEGRAPH COMPANY, AT&T BELL LABORATORIES (US) 1989-04-11 US claimed
US-20180371008-A1 METHODS OF SYNTHESIZING AND LABELING NUCLEIC ACID MOLECULES LIFE TECHNOLOGIES CORP (US) 2018-12-27 US disclosed
US-4481198-A TREATMENT OF HYPERCALCEMIC CONDITIONS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1984-11-06 US disclosed
EP-0041274-B1 FLUORESCENT COMPOSITION HAVING THE ABILITY TO CHANGE WAVELENGTHS OF LIGHT, SHAPED ARTICLE OF SAID COMPOSITION AS A LIGHT WAVELENGTH CONVERTING ELEMENT, AND DEVICE FOR CONVERTING OPTICAL ENERGY TO ELECTRICAL ENERGY USING SAID ELEMENT TEIJIN LIMITED (JP) 1984-03-14 EP disclosed