SCHEMBL5701207

SCHEMBL5701207

c1ccc(-c2ccccc2-c2cnc(-c3ccccc3-c3ccccc3)o2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.62
NPC1 O15118 4/20 0.62
ATM Q13315 1/20 0.62
TSHR P16473 3/20 0.58
ALOX15 P16050 2/20 0.58
CASP1 P29466 1/20 0.58
CREBBP Q92793 2/20 0.52
ALDH1A1 P00352 4/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
MITF O75030 1/20 0.50
PTPN1 P18031 4/20 0.48
GAA P10253 2/20 0.48
GPR55 Q9Y2T6 1/20 0.46
NOTUM Q6P988 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4343347 0.92 ALOX15 (0.69) RAB9ANPC1ATMTSHRALOX15
SCHEMBL3295181 0.92 RAB9A (0.72) RAB9ANPC1ATMTSHRALOX15
SCHEMBL1471533 0.88 RAB9A (0.77) RAB9ANPC1ATMTSHRALOX15
SCHEMBL4529408 0.79 NOTUM (0.47) RAB9ANPC1ATMTSHRALOX15
SCHEMBL11648074 0.78 ALOX15 (0.69) RAB9ANPC1ATMTSHRALOX15
SCHEMBL16587429 0.78 RAB9A (0.64) RAB9ANPC1ATMTSHRALOX15
SCHEMBL4342614 0.77 ALOX15 (0.69) RAB9ANPC1ATMTSHRALOX15
SCHEMBL10495074 0.77 RAB9A (0.66) RAB9ANPC1ATMTSHRALOX15
SCHEMBL6562916 0.77 ALOX15 (0.62) RAB9ANPC1ATMTSHRALOX15
SCHEMBL4879849 0.77 RAB9A (0.66) RAB9ANPC1ATMTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4292527-A Radiation detection system THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-09-29 US claimed
US-7151623-B2 Holographic data-storage medium TESA SCRIBOS GMBH (DE) 2006-12-19 US disclosed
EP-1395985-B1 HOLOGRAPHIC DATA-STORAGE MEDIUM TESA SCRIBOS GMBH (DE) 2006-09-06 EP disclosed
US-4292527-A Radiation detection system THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-09-29 US disclosed