Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831781 | 0.91 | TSHR (0.36) | TSHRLMNAALDH1A1 | |
| SCHEMBL13133071 | 0.90 | TSHR (0.46) | TSHRLMNAALDH1A1HCAR2CA12 | |
| SCHEMBL452059 | 0.89 | ALDH1A1 (0.52) | TSHRLMNAALDH1A1HCAR2ATM | |
| SCHEMBL19500081 | 0.89 | TSHR (0.37) | TSHRLMNAALDH1A1HCAR2ATM | |
| SCHEMBL23982990 | 0.88 | NAAA (0.52) | TSHRLMNAALDH1A1NAAA | |
| SCHEMBL10087932 | 0.87 | LMNA (0.52) | TSHRLMNAALDH1A1HCAR2ATM | |
| SCHEMBL18669142 | 0.87 | ACHE (0.41) | TSHRLMNAALDH1A1NAAA | |
| SCHEMBL1558431 | 0.87 | TSHR (0.36) | TSHRLMNAALDH1A1HPGD | |
| SCHEMBL29728734 | 0.87 | TSHR (0.36) | TSHRLMNAALDH1A1 | |
| SCHEMBL9110412 | 0.85 | TSHR (0.34) | TSHRLMNAALDH1A1NAAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898951-B1 | PHARMACEUTICAL PREPARATION CONTAINING AN ANGIOTENSIN II RECEPTOR ANTAGONIST AND A CALCIUM CHANNEL BLOCKER | DAIICHI SANKYO CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |