Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29889802 | 0.79 | PDE2A (0.46) | CYP2C19MAPT | |
| SCHEMBL5914464 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1POLBSYKCYP1A2 | |
| SCHEMBL19260458 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1POLBCYP1A2MAPK1 | |
| SCHEMBL761273 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBSYKCYP1A2 | |
| SCHEMBL11356632 | 0.69 | KDM4E (0.54) | KDM4EALDH1A1POLBCYP1A2MAPK1 | |
| SCHEMBL944044 | 0.69 | MKNK1 (0.41) | KDM4EALDH1A1POLBMETAP2TGFBR1 | |
| SCHEMBL4121667 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1POLBSYKCYP1A2 | |
| SCHEMBL2614918 | 0.69 | NOS3 (0.48) | KDM4EALDH1A1POLBCHRM4SYK | |
| SCHEMBL29031591 | 0.68 | PDE1A (0.41) | KDM4EALDH1A1POLBMAPT | |
| SCHEMBL19539213 | 0.67 | TRPA1 (0.47) | ALDH1A1CYP1A2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716115-B1 | SYNTHESIS OF ACYLOXYALKYL CARBAMATE PRODRUGS AND INTERMEDIATES THEREOF | XENOPORT INC (US) | 2013-02-27 | — | — | EP | disclosed |