Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14662316 | 0.92 | PIN1 (0.51) | PIN1MAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14661926 | 0.89 | PIN1 (0.67) | PIN1MAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14716874 | 0.88 | PIN1 (0.56) | PIN1MAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14662481 | 0.85 | MAPT (0.56) | PIN1MAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14662483 | 0.85 | MAPT (0.56) | PIN1MAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14662318 | 0.84 | PIN1 (0.49) | PIN1MAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14661878 | 0.84 | PANK3 (0.52) | PIN1TLR7CNR2APLNRCTSA | |
| SCHEMBL14717207 | 0.83 | PIN1 (0.52) | PIN1MAPTTLR7HPGDSTDP1 | |
| SCHEMBL14662703 | 0.82 | PIN1 (0.52) | PIN1MAPTATMNPSR1L3MBTL1 | |
| SCHEMBL14662374 | 0.81 | PIN1 (0.53) | PIN1HPGDSAPLNRCTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736891-B1 | SUBSTITUTED 3-(THIAZOLE-4-CARBONYL)- OR 3-(THIAZOLE-2-CARBONYL)- AMINOPROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2016-04-20 | — | — | EP | claimed |
| US-9174952-B2 | Substituted 3-thiazoloamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-11-03 | — | — | US | claimed |
| US-20130053402-A1 | SUBSTITUTED 3-THIAZOLOAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2013-02-28 | — | — | US | claimed |
| EP-2736891-B1 | SUBSTITUTED 3-(THIAZOLE-4-CARBONYL)- OR 3-(THIAZOLE-2-CARBONYL)- AMINOPROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2016-04-20 | — | — | EP | disclosed |
| US-9174952-B2 | Substituted 3-thiazoloamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-11-03 | — | — | US | disclosed |
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |
| US-20130053402-A1 | SUBSTITUTED 3-THIAZOLOAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053402-A1 | SUBSTITUTED 3-THIAZOLOAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSF, CTSS, CTSK | PIN1 2555/4885MAPT 3350/4885ATM 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.