Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14719429 | 0.83 | USP2 (0.42) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL31080015 | 0.82 | USP2 (0.50) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL13801225 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2NR1H2ESR2MAPK1 | |
| SCHEMBL120243 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL20984021 | 0.75 | USP2 (0.43) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL4767496 | 0.74 | USP2 (0.40) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL14719295 | 0.74 | USP30 (0.44) | DDB1CRBNKDM4EMAPK1GPR119 | |
| SCHEMBL17081081 | 0.73 | USP2 (0.42) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL2292608 | 0.73 | USP2 (0.52) | USP2SMN1; SMN2NR1H2DDB1CRBN | |
| SCHEMBL15248097 | 0.72 | USP2 (0.41) | USP2SMN1; SMN2NR1H2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | HTR3C, NPEPPS, RAP2C | USP2 3442/4885SMN1; SMN2 1531/4885NR1H2 2603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.