Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Palmitamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecanoic Acid Amide SCHEMBL14718933 | 1.00 | ENPP2 (0.43) | ENPP2SOAT1MEN1FAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL8121892 | 0.90 | FAAH (0.44) | ENPP2SOAT1MEN1FAAHTP53 | |
| SCHEMBL6699378 | 0.90 | FAAH (0.44) | ENPP2SOAT1MEN1FAAHTP53 | |
| SCHEMBL8660838 | 0.90 | FAAH (0.44) | ENPP2SOAT1MEN1FAAHTP53 | |
| SCHEMBL14734919 | 0.87 | BBOX1 (0.41) | ENPP2MEN1CYP2C19KMT2ADNM1 | |
| Octadecanoic Acid Amide SCHEMBL28032862 | 0.87 | SOAT1 (0.52) | ENPP2SOAT1MEN1FAAHTP53 | |
| Palmitamide SCHEMBL27903514 | 0.87 | SOAT1 (0.52) | ENPP2SOAT1MEN1FAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL1407699 | 0.82 | FAAH (0.45) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL2592430 | 0.82 | BBOX1 (0.48) | MEN1TP53KMT2ADNM1KDM4E | |
| SCHEMBL25414052 | 0.80 | DNM1 (0.60) | ENPP2MEN1KMT2ADNM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883712-B2 | Fabric softening composition | EVONIK DEGUSSA GMBH (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20130053299-A1 | Fabric Softening Composition | EVONIK DEGUSSA GMBH (DE) | 2013-02-28 | — | — | US | disclosed |