Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.63 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11773334 | 0.98 | AKR1C3 (0.61) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL5194932 | 0.88 | ABCB1 (0.52) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL269614 | 0.87 | AKR1C3 (0.63) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL30580504 | 0.87 | AKR1C3 (0.63) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL1632528 | 0.87 | ALDH1A1 (0.57) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL1567614 | 0.85 | NPC1 (0.53) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL1571262 | 0.85 | AKR1C3 (0.54) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL2839286 | 0.85 | KCNMA1 (0.53) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL28588348 | 0.84 | AKR1C3 (0.54) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL3885239 | 0.84 | AKR1C3 (0.51) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880762-B | Triacylamine derivatives containing 1,8-naphthalimide as well as preparation method and application thereof | 河北农业大学 | 2023-02-21 | — | — | CN | claimed |
| CN-113880762-A | 1, 8-naphthalimide-containing triacylamine derivatives, and preparation method and application thereof | 河北农业大学 | 2022-01-04 | — | — | CN | claimed |
| CN-110747489-B | Electroreduction preparation method of intermediate of anticancer drug gefitinib and analogue thereof | 湖南大学 | 2021-05-07 | — | — | CN | claimed |
| CN-110747489-A | Electroreduction preparation method of intermediate of anticancer drug gefitinib and analogue thereof | 湖南大学 | 2020-02-04 | — | — | CN | claimed |
| CN-107188841-B | A kind of synthetic method of asymmetry diaryl list selenide compound | 温州医科大学 | 2019-07-16 | — | — | CN | claimed |
| CN-109553534-A | A kind of preparation method of 2- nitro -4- methoxy benzoic acid | 常州大学 | 2019-04-02 | — | — | CN | claimed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | claimed |
| EP-4069252-B1 | PDIA4 INHIBITORS AND USE THEREOF FOR INHIBITING SS-CELL PATHOGENESIS AND TREATING DIABETES | ACADEMIA SINICA (CN) | 2025-12-10 | — | — | EP | disclosed |
| US-12297207-B2 | Maytansinoid derivatives, conjugates thereof, and methods of use | REGENERON PHARMACEUTICALS, INC. (US) | 2025-05-13 | — | — | US | disclosed |
| CN-119841822-A | Pyrimido [5,4-c ] quinoline compound, preparation method, pharmaceutical composition and application thereof | 苏州施安鼎泰生物医药技术有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119285675-A | Self-assembled hole transport material, photoelectric device, and preparation method and application thereof | 天合光能股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-118307594-A | Tricarbazole amine-based compound, self-assembled hole transport material containing compound and application of self-assembled hole transport material in perovskite solar cell | 天合光能股份有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-115322158-B | As KRASG12CSubstituted quinazoline compounds of protein inhibitor | 江南大学 | 2024-04-30 | — | — | CN | disclosed |
| EP-0028473-B1 | CHLORO- AND ALKOXY-SUBSTITUTED-2,4-DIAMINOQUINAZOLINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER INC. (US) | 1985-01-09 | — | — | EP | disclosed |
| US-4377581-A | ANTIHYPERTENSIVE AGENTS | PFIZER INC. (US) | 1983-03-22 | — | — | US | disclosed |
| US-4351940-A | Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4287341-A | USEFUL AS ANTIHYPERTENSIVE AGENTS | PFIZER INC. (US) | 1981-09-01 | — | — | US | disclosed |
| EP-0028473-A1 | Chloro- and alkoxy-substituted-2,4-diaminoquinazolines and pharmaceutical compositions containing them | PFIZER INC. (US) | 1981-05-13 | — | — | EP | disclosed |
| US-4111937-A | IODINATED ANILIC ACIDS | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4031088-A | Iodinated anilic acids | STERLING DRUG INC. (US) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297207-B2 | Maytansinoid derivatives, conjugates thereof, and methods of use | SLC10A1, HNMT, OGFR | AKR1C3 428/4885AKR1C2 417/4885AKR1B10 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.