Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720267 | 0.82 | AAK1 (0.45) | RAB9ANPC1TP53POLB | |
| SCHEMBL2299342 | 0.82 | KMT2A (0.44) | KMT2ARAB9ANPC1MEN1EPHX2 | |
| SCHEMBL14720417 | 0.78 | HDAC3 (0.41) | KMT2ARAB9ANPC1MEN1HPGD | |
| SCHEMBL14720616 | 0.74 | LIMK2 (0.36) | KMT2AMEN1 | |
| SCHEMBL7401491 | 0.74 | KMT2A (0.87) | KMT2ARAB9ANPC1MEN1EPHX2 | |
| SCHEMBL14720415 | 0.72 | DRD2 (0.38) | KMT2ARAB9AMEN1HPGDPOLB | |
| SCHEMBL11520494 | 0.70 | RAB9A (0.97) | KMT2ARAB9ANPC1MEN1EPHX2 | |
| SCHEMBL14687969 | 0.68 | KMT2A (0.74) | KMT2ARAB9ANPC1MEN1EPHX2 | |
| SCHEMBL16825887 | 0.68 | KMT2A (0.74) | KMT2ARAB9ANPC1MEN1EPHX2 | |
| SCHEMBL14720555 | 0.68 | FASN (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |